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Scientific Articles
Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase
May 07 2018Cancer Research

Naoya Matsunaga, Takashi Ogino, Yukinori Hara, Takahiro Tanaka, Satoru Koyanagi and Shigehiro Ohdo

The highly metastatic nature of uterine cervical/endometrial cancer displaying tumor-related leukocytosis: clinical and preclinical investigations
May 11 2018Clinical Cancer Research

Tomoyuki Sasano, Seiji Mabuchi, Katsumi Kozasa, Hiromasa Kuroda, Mahiru Kawano, Ryoko Takahashi, Naoko Komura, Eriko Yokoi, Yuri Matsumoto, Kae Hashimoto, Kenjiro Sawada, Eiichi Morii and Tadashi Kimura

Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease
May 17 2018Nature Communications

Masayoshi Ohkuro, Jun-Dal Kim, Yoshikazu Kuboi, Yuki Hayashi, Hayase Mizukami, Hiroko Kobayashi-Kuramochi, Kenzo Muramoto, Manabu Shirato, Fumiko Michikawa-Tanaka, Jun Moriya, Teruya Kozaki, Kazuma Takase, Kenichi Chiba, Kishan Lal Agarwala, Takayuki Kimura, Makoto Kotake, Tetsuya Kawahara, Naoki Yoneda, Shinsuke Hirota, Hiroshi Azuma, Nobuko Ozasa-Komura, Yoshiaki Ohashi, Masafumi Muratani, Keiji Kimura, Ieharu Hishinuma & Akiyoshi Fukamizu

High-fat Diet-induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
May 18 2018Clinical Cancer Research

Takuji Hayashi, Kazutoshi Fujita, Satoshi Nojima, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Yoshiyuki Yamamoto, Toshiro Kinouchi, Kyosuke Matsuzaki, Kentaro Jingushi, Taigo Kato, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Maria Del Carmen Rodriguez Pena, Jennifer B Gordetsky, Eiichi Morii, Kazutake Tsujikawa, George J Netto and Norio Nonomura

Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles
May 22 2018Cell Reports

Masahiro Tsuchiya, Shigenori Sekiai, Hiroyasu Hatakeyama, Masashi Koide, Chayanit Chaweewannakorn, Fukie Yaoita, Koichi Tan-No, Keiichi Sasaki, Makoto Watanabe, Shunji Sugawara, Yasuo Endo, Eiji Itoi, Yoshihiro Hagiwara, Makoto Kanzaki

Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response
May 23 2018Leukemia

Kana Sakamoto, Ryohei Katayama, Reimi Asaka, Seiji Sakata, Satoko Baba, Hideki Nakasone, Sumie Koike, Naoko Tsuyama, Akito Dobashi, Makoto Sasaki, Ryo Ichinohasama, Emi Takakuwa, Rie Yamazaki, Jun Takizawa, Takahiro Maeda, Miwako Narita, Koji Izutsu, Yoshinobu Kanda, Koichi Ohshima & Kengo Takeuchi

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
Sep 20 2018Cells

Takaaki Yasuhara, Reona Kato, Yoshihiko Hagiwara, Bunsyo Shiotani, Motohiro Yamauchi, Shinichiro Nakada, Atsushi Shibata, Kiyoshi Miyagawa

Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction
May 31 2018Blood

Nagaharu Tsukiji Ph.D., Osamu Inoue M.D., Ph.D, Mitsuru Morimoto Ph.D., Norifumi Tatsumi Ph.D., Hiroaki Nagatomo Ph.D., Koji Ueta M.D., Toshiaki Shirai Ph.D., Tomoyuki Sasaki Ph.D., Shimon Otake M.D., Shogo Tamura Ph.D., Toshiaki Tachibana Ph.D, Masataka Okabe M.D., Ph.D, Masanori Hirashima M.D., Ph.D, Yukio Ozaki M.D., Ph.D and Katsue Suzuki-Inoue M.D., Ph.D

SIRT2‐mediated inactivation of p73 is required for glioblastoma tumorigenicity
Sep 13 2018EMBO Reports

Kosuke Funato, Tomoatsu Hayashi, Kanae Echizen, Lumi Negishi, Naomi Shimizu, Ryo Koyama‐Nasu, Yukiko Nasu‐Nishimura, Yasuyuki Morishita, Viviane Tabar, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Nobuhito Saito, Tetsu Akiyama

Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment
Jun 19 2018Clinical Cancer Research

Takuya Kato, Kazuhiro Noma, Toshiaki Ohara, Hajime Kashima, Yuki Katsura, Hiroaki Sato, Satoshi Komoto, Ryoichi Katsube, Takayuki Ninomiya, Hiroshi Tazawa, Yasuhiro Shirakawa and Toshiyoshi Fujiwara

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