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Scientific Articles
De novo PHACTR1 mutations in West syndrome and their pathophysiological effects
Sep 26 2018Brain

Nanako Hamada  Shunsuke Ogaya  Mitsuko Nakashima  Takuma Nishijo  Yuji Sugawara Ikuko Iwamoto  Hidenori Ito  Yuki Maki  Kentaro Shirai  Shimpei Baba  Koichi Maruyama Hirotomo Saitsu  Mitsuhiro Kato  Naomichi Matsumoto  Toshihiko Momiyama Koh-ichi Nagata

A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells
Mai 17 2018Cell Host & Microbe

Yoichiro Fujioka, Shinya Nishide, Toyoyuki Ose, Tadaki Suzuki, Izumi Kato, Hideo Fukuhara, Mari Fujioka, Kosui Horiuchi, Aya O. Satoh, Prabha Nepal, Sayaka Kashiwagi, Jing Wang, Mika Horiguchi, Yuko Sato, Sarad Paudel, Asuka Nanbo, Tadaaki Miyazaki, Hideki Hasegawa, Katsumi Maenaka, Yusuke Ohba

High-fat Diet-induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
Mai 18 2018Clinical Cancer Research

Takuji Hayashi, Kazutoshi Fujita, Satoshi Nojima, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Yoshiyuki Yamamoto, Toshiro Kinouchi, Kyosuke Matsuzaki, Kentaro Jingushi, Taigo Kato, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Maria Del Carmen Rodriguez Pena, Jennifer B Gordetsky, Eiichi Morii, Kazutake Tsujikawa, George J Netto and Norio Nonomura

Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles
Mai 22 2018Cell Reports

Masahiro Tsuchiya, Shigenori Sekiai, Hiroyasu Hatakeyama, Masashi Koide, Chayanit Chaweewannakorn, Fukie Yaoita, Koichi Tan-No, Keiichi Sasaki, Makoto Watanabe, Shunji Sugawara, Yasuo Endo, Eiji Itoi, Yoshihiro Hagiwara, Makoto Kanzaki

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17
Mai 22 2018The Journal of Cell Biology

Takahide Matsui, Peidu Jiang, Saori Nakano, Yuriko Sakamaki, Hayashi Yamamoto, Noboru Mizushima

DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway
Mai 31 2018Cell Death & Differentiation

Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Tasuku Nakabori, Satoshi Tanaka, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi & Tetsuo Takehara

Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction
Mai 31 2018Blood

Nagaharu Tsukiji Ph.D., Osamu Inoue M.D., Ph.D, Mitsuru Morimoto Ph.D., Norifumi Tatsumi Ph.D., Hiroaki Nagatomo Ph.D., Koji Ueta M.D., Toshiaki Shirai Ph.D., Tomoyuki Sasaki Ph.D., Shimon Otake M.D., Shogo Tamura Ph.D., Toshiaki Tachibana Ph.D, Masataka Okabe M.D., Ph.D, Masanori Hirashima M.D., Ph.D, Yukio Ozaki M.D., Ph.D and Katsue Suzuki-Inoue M.D., Ph.D

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Sep 11 2018Cell Reports

Ryutaro Ikegami, Ippei Shimizu, Takeshi Sato, Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Ji Li, Takayuki Wakasugi, Yasuhiko Minokoshi, Shiki Okamoto, Eiichi Hinoi, Søren Nielsen, Naja Zenius Jespersen, Camilla Scheele, Tomoyoshi Soga, Tohru Minamino

TRPM2 exacerbates central nervous system inflammation in experimental autoimmune encephalomyelitis by increasing production of CXCL2 chemokines
Sep 10 2018The Journal of Neuroscience

Masato Tsutsui, Ryo Hirase, Sakie Miyamura, Kazuki Nagayasu, Takayuki Nakagawa, Yasuo Mori, Hisashi Shirakawa and Shuji Kaneko

Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance
Sep 06 2018The Journal of Cell Biology

Akari Hagiwara, Yosuke Kitahara, Chad Paul Grabner, Christian Vogl, Manabu Abe, Ryo Kitta, Keisuke Ohta, Keiichiro Nakamura, Kenji Sakimura, Tobias Moser, Akinori Nishi, and Toshihisa Ohtsuka

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