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Transformed African Green Monkey Kidney Fibroblast Cells (COS-7 Line)
The COS-7 cell line was derived by Yakov Gluzman in the early 1980s from the previously established CV-1 African green monkey kidney line by transformation of the normal cells with an origin defective mutant of simian virus 40 (SV40) that codes for the wild-type virus T-antigen. The fibroblast line grows adherently to glass and plastic in culture and is generally utilized as a transfection host.
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