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The CV-1 cell line was initiated in March of 1964 by F. C. Jensen and his colleagues with a tissue section excised from the kidney of a normal adult male African green monkey (Cercopithecus aethiops). The popular fibroblast line was originally utilized in research focusing on the transformation of the cancer-causing Rous sarcoma virus (RSV), but now is a very useful host for acquired immunodeficiency disease (AIDS) research, as well as transfection experiments with simian virus 40 (SV40) and recombinant plasmid vectors.
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