Transformed African Green Monkey Kidney Fibroblast Cells (COS-7 Line)
The CV-1 cell line, which is permissive for lytic growth of simian virus 40 (SV40), was established in the 1960s from the kidney of an African green monkey. The COS-7 line was developed from that line about 20 years later by Yakov Gluzman via transformation with an origin defective mutant of SV40 that codes for the wild-type virus T-antigen.
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