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CRE BAG 2 is a fibroblast cell line that was developed from the NIH 3T3 embryonic Swiss mouse cell line, which was transfected with Moloney murine leukemia virus-derived proviral genomes carrying complementary mutations in the gag-pol or env regions. The genomes were altered at the 3' end of the provirus and contained a deletion of the psi sequence needed for the efficient encapsidation of retroviral genomes into virions.
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